An Unusual Cause of Elevated Values on Liver Function Tests in a Liver Transplant Patient


Ankur Jain, MD; Amandeep Sahota, MD; Najeeb S Alshak, MD; Jim K Tung, MD

Spring 2009 - Volume 13 Number 2


Biliary obstruction and rejection are two of the most common causes of abnormal findings on liver function tests (LFTs) in patients who have already undergone liver transplantation. Here we present a post-transplant patient with jaundice. Tests showed that he had no hepatitis B surface antigen before transplantation; he received a core antibody-negative liver. He was not previously vaccinated against hepatitis B, however, and acute hepatitis B was found to be the cause of his increased values on LFTs. His case demonstrates the need to keep a broad differential during laboratory workup of such patients and to vaccinate those patients at risk for acquiring hepatitis B or developing complications.



Click here to join the eTOC list or text ETOC to 22828. You will receive an email notice with the Table of Contents of The Permanente Journal.


27,000 print readers per quarter, 15,350 eTOC readers, and in 2018, 2 million page views of TPJ articles in PubMed from a broad international readership.


Indexed in MEDLINE, PubMed Central, HINARI, EMBASE, EBSCO Academic Search Complete, rdrb, CrossRef, and SciVerse/Scopus.




ISSN 1552-5767 Copyright © 2020

All Rights Reserved.